News
Updates from the Ismail Lab and our collaborators.
The Ismail Lab has been awarded a 5-year Canadian Institutes of Health Research (CIHR) grant to study targeting MAEA to overcome PARP inhibitor resistance in high-grade serous ovarian cancer; exciting science is underway!
CRINA profile interview with Dr. Ismail on DNA repair, chemotherapy resistance, and the lab's approach to genome integrity research.
Huge congratulations to Rama for winning the Best Oral Presentation Award at the 7th Canadian Symposium on Telomeres and Genome Integrity in Victoria, BC!
Congratulations to Jana Sharaby on receiving the CRINA / Alberta Cancer Foundation (ACF) Summer Studentship, and to Jarin Tasnim on being awarded the FoMD Summer Studentship! Fantastic work, Jana and Jarin!
Congratulations to Rama on being awarded the CIHR Master’s Studentship! Additionally, she received a CRINA Travel Award to support her trip to present at the 7th Canadian Symposium on Telomeres and Genome Integrity in Victoria, BC. Fantastic achievements, Rama!
Eli was recognized with an award for being the Best Trainee Questioner for her insightful and relevant questions during the meeting discussions. Great job driving scientific discussion!
Eli received a Conference Travel Award from the organizers to attend and present at the 7th DNA Repair/Replication Structures & Cancer Conference in Playa Mujeres, Mexico. Congratulations, Eli!
Our lab is thrilled to receive a three-year Dr. Heleen and Rod McLeod Operating Grant in Hematological Cancers from the Cancer Research Institute of Northern Alberta (CRINA)! This major funding will support our ongoing research into the mechanisms of drug resistance in Multiple Myeloma.
University of Alberta coverage of our Science Advances study on MAEA, a CTLH E3 ligase component that protects replication forks and may help reverse chemotherapy resistance. PhD student Elham Zeinali is featured alongside principal investigator Dr. Ismail Ismail.
Huge congratulations to Eli for receiving the prestigious Rachel Mandel Scholarship in Lymphoma and Other Blood Cancers! Well deserved!
Huge congratulations to Dr. Fatemeh Mashayekhi on receiving the Department of Oncology Achievement Award in recognition of her outstanding paper published in Cell Reports! Well deserved, Dr. Fatemeh!
A major milestone month! Congratulations to Eli on having her first-author research paper accepted for publication in the prestigious journal Science Advances! Excellent work, Eli!
The lab is excited to announce that we have been awarded an Innovation Operating Grant from the Women and Children’s Health Research Institute (WCHRI)! This funding will support our research investigating the role of DNA repair mechanisms in overcoming drug resistance in ovarian cancer.
Congratulations to Rama on receiving the Yau Family Foundation Scholarship!
We held a farewell gathering to celebrate Fatemeh as she embarks on the next stage of her career! We will miss you, Fatemeh, and wish you all the best in your postdoctoral fellowship at the University of Calgary!
A massive congratulations to Dr. Fatemeh on successfully defending her PhD thesis! To top off an incredible month, her first-author paper was accepted for publication in Cell Reports. Congratulations, Dr. Fatemeh!
Huge congratulations to Dr. Andrew Locke on successfully defending his PhD thesis! Outstanding achievement, Dr. Andrew!
Congratulations to Fatemeh on having her second first-author paper accepted for publication in the Journal of Biological Chemistry (JBC)!
Congratulations to Eli on being awarded the Yau Family Foundation Scholarship!
The Ismail Lab is honoured to receive the Peter Lougheed Award from the Calgary Foundation to support our research on MAEA's role in maintaining genome stability.
Congratulations to Andrew on having his second first-author paper accepted for publication in the Journal of Biological Chemistry (JBC)! Outstanding work, Andrew
The Ismail Lab, together with the Chan and Gamper labs, has been awarded a Canada Foundation for Innovation (CFI) grant to acquire a spinning-disk microscope, enhancing our capabilities for functional analysis of cellular mechanisms via live-cell time-lapse confocal microscopy.
Congratulations to Taylor Lovsund on having her review article accepted for publication in Cells! Well done, Taylor!
The Ismail Lab has been awarded one-year bridge funding from the Cancer Research Institute of Northern Alberta (CRINA) to advance our research into the mechanistic insights of DNA double-strand break repair.
Congratulations to Dr. Ajit Sharma on having his protocol paper, "Quantification of protein enrichment at site-specific DNA double-strand breaks by chromatin immunoprecipitation in cultured human cells," accepted for publication in STAR Protocols! Well done, Dr. Ajit!
The Ismail Lab has been awarded a Canada Foundation for Innovation (CFI) grant to acquire the Cytation 10 High-Content Imager, enabling advanced long-term time-lapse imaging to study cellular fate and dynamics.
Congratulations to Dr. Ajit Sharma on having his protocol paper accepted for publication in STAR Protocols! Well done, Dr. Ajit!
Huge congratulations to Andrew Locke on receiving the prestigious Rachel Mandel Scholarship in Lymphoma and Other Blood Cancers! Exceptionally well-deserved, Andrew!
Congratulations to Jana Ali on the acceptance of her review article, "The Role of DNA Repair in Genomic Instability of Multiple Myeloma," for publication in the International Journal of Molecular Sciences (IJMS)! Well done, Jana!
Congratulations to Dr. Amira Fitieh on having her paper accepted for publication in the prestigious journal Cell Reports! Well done, Dr. Amira!
Congratulations to Andrew Locke on receiving the MedStar Graduate Student Award in recognition of his outstanding publication in Nucleic Acids Research! Fantastic work, Andrew!
Congratulations to Dr. Andrew Locke on receiving the Department of Oncology Achievement Award in recognition of his publication in Nucleic Acids Research! Fantastic work, Andrew!
Congratulations to Dr. Amira Fitieh on having her review article accepted for publication in the International Journal of Molecular Sciences (IJMS)! Well done, Dr. Amira!
Major milestone! Congratulations to Andrew Locke on having his first-author research paper, "SUMOylation mediates CtIP's functions in DNA end resection and replication fork protection," accepted for publication in the prestigious journal Nucleic Acids Research! Outstanding work, Andrew!
The Ismail Lab has been awarded a 5-year Canadian Institutes of Health Research (CIHR) grant to study the regulation of homologous recombination by the ubiquitin ligase RNF138.
The Ismail Lab has been awarded a 5-year NSERC Discovery Grant to support our research investigating the role of the Small Ubiquitin-like Modifier (SUMO) in DNA end resection.
The Ismail Lab has been awarded a two-year operating grant from the Cancer Research Society to support our research on Targeting DNA Repair Pathways for Multiple Myeloma Treatment.