About

About the lab

A research group focused on how cells maintain genome integrity, and how cancer hijacks those pathways.

Overview

Our research sits at the intersection of genome integrity, protein regulation, and precision oncology. We use advanced biochemical, microscopic imaging, proteomic, and cellular models to understand how cancer cells exploit DNA repair pathways to survive treatment, with the ultimate goal of developing smarter, resistance-defying therapies.

Dr. Ismail Ismail is an Associate Professor in the Department of Oncology in the Faculty of Medicine & Dentistry at the University of Alberta, based at the Cross Cancer Institute.

Training

  • PhD (Clinical Chemistry and Transfusion Medicine), Göteborg University, Sweden
  • BSc (Biophysics, distinction with honour), Cairo University, Egypt

Teaching

  • ONCOL 425/525: Advanced Topics in Cancer Research
  • ONCOL 520: Tumor Biology
  • ONCOL 570: Directed Reading in Experimental Oncology

Research keywords

DNA repair · DNA damage · Multiple myeloma · Post-translational modifications · Replication stress response . Ovarian cancer . Drug resistance

In the media

Meet a researcher: Ismail Ismail: CRINA interview on the lab's work in genome integrity and cancer therapy resistance.